Reliability Options: Can They Deliver on Their Promises?

Nanopharmaceuticals for improved topical vaginal therapy: can they deliver?

Nanopharmaceuticals have the potential to revolutionise medical treatment by permitting the design of more potent, less toxic "smart" therapeutics, ultimately leading to personalised medicine. This review summarises the challenges and potential uses of nanodelivery system for the topical drug therapy of vaginal diseases. The vaginal route of drug administration remains a challenge in the develo...

Great expectations: can artificial molecular machines deliver on their promise?

The development and fabrication of mechanical devices powered by artificial molecular machines is one of the contemporary goals of nanoscience. Before this goal can be realized, however, we must learn how to control the coupling/uncoupling to the environment of individual switchable molecules, and also how to integrate these bistable molecules into organized, hierarchical assemblies that can pe...

Twenty years of failure - Why GM crops have failed to deliver on their promises

The Reliability of Computer Predictions: Can They Be Trusted?

The issue of reliability of computer predictions of physical events is examined as the goal of verification and validation processes. It is argued that verification, both solution and code verification, can be carried out with a high degree of confidence, even though much remains to be done to improve and advance verification procedures. It is validation of mathematical models that stands as th...

Can private equity deliver on equity?

a Save the Children UK, 1 St John’s Lane, London, EC1M 4AR, England. Correspondence to Giorgio Cometto (e-mail: [email protected]). In June 2009, a new Health in Africa Fund was launched by the International Finance Corporation (IFC), the branch of The World Bank group mandated with supporting and expanding the private for-profit sector. This Fund will be managed by Aureos Capital, a p...